Molecular Formula | C26H31N3O3 |
Molar Mass | 433.55 |
Density | 1.142±0.06 g/cm3(Predicted) |
Boling Point | 630.7±55.0 °C(Predicted) |
pKa | 14.24±0.46(Predicted) |
Storage Condition | 2-8°C |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.307 ml | 11.533 ml | 23.066 ml |
5 mM | 0.461 ml | 2.307 ml | 4.613 ml |
10 mM | 0.231 ml | 1.153 ml | 2.307 ml |
5 mM | 0.046 ml | 0.231 ml | 0.461 ml |
biological activity | ML188, a probe that is also a selective non-covalent SARS-CoV 3CLpro inhibitor, the IC50 was 1.5 μm. Has antiviral activity. |
Cell Line: | Vero E6 cells (mock-infected or infected with SARS-CoV) |
Concentration: | 3, 4, 5, 8,10, 15, 20, 30 μM |
Incubation Time: | 48 hour |
Result: | Against mock-infected and SARS-CoV infected cells. |